KMID : 1039320210210010069
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Journal of Liver Cancer 2021 Volume.21 No. 1 p.69 ~ p.75
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A Case of Lymphocyte-Rich Hepatocellular Carcinoma in a Patient Who Was Treated for Colon Cancer
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Song Jae-Won
Chun Ho-Soo Lee Jae-Seung Lee Hye-Won Kim Beom-Kyung Kim Seung-Up Park Jun-Yong Ahn Sang-Hoon Park Young-Nyun Han Dai-Hoon Kim Do-Young
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Abstract
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Hepatocellular carcinoma (HCC) primarily originates in the liver with hepatic differentiation. However, HCCs are not homogenous, and approximately 35% of HCC cases are classified as histopathological variants that present distinct pathologic characteristics. In particular, the lymphocyte-rich variant is the rarest subtype accounting for less than 1% of HCCs, which is not well known to date about molecular features and pathophysiology. Herein, we present a case of a patient who was suspected of metastatic liver cancer and confirmed as lymphocyte-rich HCC pathologically. A 78-year-old woman who underwent a right hemicolectomy for colon cancer was referred to our hospital for a newly detected liver mass. We could not make a decision because of insufficient evidence for diagnosis from imaging studies. After resection, we found that it was a lymphocyte-rich HCC. The pathologic features and prognostic trends of this subtype are also discussed.
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KEYWORD
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Hepatocellular carcinoma, Hepatocellular carcinoma variants, Lymphocyte-rich subtype
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